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Home Antibody All anti-ZC3H12B antibodies

Anti-ZC3H12B Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306954 Rabbit Polyclonal ZC3H12B Antibody 100ug $325 3-7 Days
LC423209 ZC3H12B HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
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Also for ZC3H12B (NM_001010888)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Request Antibody

OriGene Data

ImmunogenZC3H12B antibody was raised against a 17 amino acid peptide near the amino terminus of human ZC3H12B.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsELISA, WB: 1 ug/ml, IHC: 5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens zinc finger CCCH-type containing 12B (ZC3H12B)
Alternative NameCXorf32; MCPIP2
Database LinkNP_001010888
Entrez Gene 340554 Human
Entrez Gene 547176 Mouse
Entrez Gene 296864 Rat
FunctionZC3H12B, also known as MCPIP2, is a member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. The function of ZC3H12B is not well understood. Unlike other members of the ZC3H12 family, ZC3H12B has a RasGEF domain at the C-terminal of the zinc finger motif, suggesting its potential involvement in Ras-mediated signal transduction. It is highly expressed in brain, thymus, and testis, but unlike ZC3H12A and ZC3H12C, not expressed in macrophages after treatment with lipopolysaccharide (LPS).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of ZC3H12B in mouse brain tissue lysate with ZC3H12B antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of ZC3H12B in human brain tissue with ZC3H12B antibody at 5 ug/mL.
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