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Anti-KLF4 Antibody

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IHC(1)

OriGene Data

Immunogen	KLF4 antibody was raised against a 20 amino acid peptide near the carboxy terminus of human KLF4.
Clone Name		Isotype	IgG
Species Reactivity	Human, Mouse, Rat	Concentration	1ug/ul
Guaranteed Application *	WB, IHC	Suggested Dilutions	ELISA, WB: 1 - 2 ug/ml, IHC: 5 ug/ml
Buffer	PBS containing 0.02% sodium azide.
Purification	Affinity chromatography purified via peptide column (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens Kruppel-like factor 4 (gut) (KLF4)
Alternative Name	EZF; GKLF
Database Link	NP_004226
Function	KLF4 is a transcription factor that functions as both a transcriptional activator and repressor to regulate proliferation and differentiation of multiple cell types. The role of KLF4 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing KLF4 and the transcription factors POU5F1, Sox2, and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing KLF4, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine. KLF4 interacts directly with POU5F1 and Sox2 in iPS and ES cells and activates the target gene NANOG.
Related Pathway

Related Lysate from OriGene • Transient overexpression lysate of Kruppel-like factor 4 (gut) (KLF4) • Transient overexpression lysate of Kruppel-like factor 4 (gut) (KLF4) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • KLF4 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • KLF4 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Klf4 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • KLF4 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Klf4 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens Kruppel-like factor 4 (gut) (KLF4) as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens Kruppel-like factor 4 (gut) (KLF4) as transfection-ready DNA • Lenti ORF clone of Human Kruppel-like factor 4 (gut) (KLF4), mGFP tagged • GFP-tagged ORF clone of Homo sapiens Kruppel-like factor 4 (gut) (KLF4) as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens Kruppel-like factor 4 (gut) (KLF4) as transfection-ready DNA • Lenti ORF clone of Human Kruppel-like factor 4 (gut) (KLF4) , Myc-DDK-tagged • Lenti ORF clone of Human Kruppel-like factor 4 (gut) (KLF4) , Myc-DDK-tagged • Lenti ORF clone of Human Kruppel-like factor 4 (gut) (KLF4), mGFP tagged Related cDNA Clones • Homo sapiens Kruppel-like factor 4 (gut) (KLF4) as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)