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Home Antibody All anti-GATA3 antibodies

Anti-GATA3 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306922
  • Rabbit Polyclonal GATA3 Antibody
100ug $325 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IHC(1)

OriGene Data

ImmunogenGATA3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human GATA3.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsELISA, WB: 1 - 2 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens GATA binding protein 3 (GATA3), transcript variant 1
Alternative NameHDR; HDRS
Database LinkNP_001002295
Entrez Gene 2625 Human
Entrez Gene 14462 Mouse
Entrez Gene 85471 Rat
FunctionGATA3 is a zinc finger transcription factor that was first recognized as a possible determinant of T cell development. Later studies demonstrated that it is expressed in trophoblast giant cells and regulates trophoblast-specific genes during development. Specifically, GATA3 is selectively expressed in the trophectoderm of the peri-implantation embryo and regulates CDX2, which is required for the transcriptional repression of the POU5F1/Oct4 and NANOG genes and is thus essential for the segregation of the inner cell mass and trophectoderm at the blastocyst stage. Decreased or null-expression expression of GATA3 has also been suggested to play a major role in the development and progression of luminal breast cancer.
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayES Cell Differentiation/IPSAdult stem cellsTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of GATA3 in human brain tissue lysate with GATA3 antibody at (A) 1 and (B) 2 ug/mL.
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Immunohistochemistry of GATA3 in rat brain tissue with GATA3 antibody at 2.5 ug/mL.
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