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Home Antibody All anti-ARHGAP18 antibodies

Anti-ARHGAP18 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306917
  • Rabbit Polyclonal ARHGAP18 Antibody
100ug 325 In Stock
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WB(1)
IF(1)

OriGene Data

ImmunogenARHGAP18 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ARHGAP18.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, ICC: 2.5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens Rho GTPase activating protein 18 (ARHGAP18)
Alternative NamebA307O14.2; MacGAP; SENEX
Database LinkNP_277050
Entrez Gene 93663 Human
Entrez Gene 73910 Mouse
Entrez Gene 293947 Rat
FunctionARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins known to be encoded in the human genome. Rho proteins belong to the Ras superfamily that is composed of over 50 members divided into six families, including Ras, Sar, Rho, Ran, Rab and Arf. Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. ARHGAP18 is linked to Ras, and thus, to EGFR-mediated proliferation, migration and differentiation. ARHGAP18 is precisely contained within chromosome 6q22-24, which has been shown to be linked to schizophrenia, suggesting that ARHGEP18 may play a role in this condition.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of ARHGAP18 in 3T3 cell lysate with ARHGAP18 antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunocytochemistry of ARHGAP18 in 3T3 cells with ARHGAP18 antibody at 2.5 ug/mL.

 

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