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Home Antibody All anti-Pkdcc antibodies

Anti-Pkdcc Antibody

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SKU Description Amount Price Availability*  
TA306903
  • Rabbit Polyclonal VLK Antibody
100ug $325 In Stock
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenVLK antibody was raised against a 15 amino acid peptide from near the center of human VLK.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot Dependent
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens protein kinase domain containing, cytoplasmic (PKDCC)
Alternative NameSGK493; Vlk
Database LinkNP_612379
FunctionVLK was identified as a novel protein kinase that was induced after the differentiation of cultured embryonic stem cells into mesendoderm. It has no homologs in invertebrates, but is highly conserved in vertebrate species although it does not belong to any known protein kinase groups. VLK is initially expressed in E-cadherin-positive anterior visceral endoderm and mesendoderm, but its expression is later confined to E-cadherin-negative mesenchyme. It is enriched in the Golgi apparatus and is thought to regulate the rate of protein export from the Golgi. Targeted disruption of VLK in mice leads to a defect in lung development and neonatal lethality. It has been suggested that mutations in VLK may be associated with the allergic condition atopy.
Related Pathway

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WB Image
Western blot analysis of VLK in human lung tissue lysate with VLK antibody at 1 ug/mL.
IHC Image
Immunohistochemistry of VLK in rat lung tissue with VLK antibody at 2.5 ug/mL.
IF Image
Immunofluorescence of VLK in rat lung tissue with VLK antibody at 5 ug/mL.

 

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