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Home Antibody All anti-Pkdcc antibodies

Anti-Pkdcc Antibody


Specifications Citations (2) Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306903 Rabbit Polyclonal VLK Antibody 100ug $325 In Stock
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OriGene Data

ImmunogenVLK antibody was raised against a 15 amino acid peptide from near the center of human VLK.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 5 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens protein kinase domain containing, cytoplasmic (PKDCC)
Alternative NameSGK493; Vlk
Database LinkNP_612379
Entrez Gene 91461 Human
Entrez Gene 106522 Mouse
Entrez Gene 313860 Rat
FunctionVLK was identified as a novel protein kinase that was induced after the differentiation of cultured embryonic stem cells into mesendoderm. It has no homologs in invertebrates, but is highly conserved in vertebrate species although it does not belong to any known protein kinase groups. VLK is initially expressed in E-cadherin-positive anterior visceral endoderm and mesendoderm, but its expression is later confined to E-cadherin-negative mesenchyme. It is enriched in the Golgi apparatus and is thought to regulate the rate of protein export from the Golgi. Targeted disruption of VLK in mice leads to a defect in lung development and neonatal lethality. It has been suggested that mutations in VLK may be associated with the allergic condition atopy.
Related PathwayProtein KinaseDruggable Genome

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WB Image
Western blot analysis of VLK in human lung tissue lysate with VLK antibody at 1 ug/mL.

WB Image
Figure from citation: Western Blot of Pkdcc(VLK) protein level by using anti-Pkdcc antibody in lysates and CM of brefeldin A treated human HepG2 cells. View Citation

IHC Image
Immunohistochemistry of VLK in rat lung tissue with VLK antibody at 2.5 ug/mL.

IF Image
Immunofluorescence of VLK in rat lung tissue with VLK antibody at 5 ug/mL.


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