Home Antibody All anti-PPAPDC3 antibodies
Also for PPAPDC3 (NM_032728)
|PPAPDC3 antibody was raised against a 19 amino acid peptide from near the amino of terminus human PPAPDC3.|
|Human, Mouse, Rat
||WB: 1 - 2 ug/ml, IF: 20 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens phosphatidic acid phosphatase type 2 domain containing 3 (PPAPDC3)|
Entrez Gene 84814 Human
Entrez Gene 227721 Mouse
Entrez Gene 296635 Rat
|PPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It is a member of the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR. PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues. Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis.|
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Western blot analysis of PPAPDC3 in mouse heart tissue lysate with PPAPDC3 antibody at (A) 1 and (B) 2 µg/ml.
Immunofluorescence of PPAPDC3 in mouse heart tissue with PPAPDC3 antibody at 20 ug/mL.