Home Antibody All anti-PPAPDC2 antibodies
Also for PPAPDC2 (NM_203453)
|PPAPDC2 antibody was raised against a 13 amino acid peptide from near the carboxy terminus human PPAPDC2.|
|Human, Mouse, Rat
||WB: 1 ug/ml, IF: 20 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens phosphatidic acid phosphatase type 2 domain containing 2 (PPAPDC2)|
|bA6J24.6; PDP1; PSDP|
Entrez Gene 403313 Human
Entrez Gene 74411 Mouse
Entrez Gene 619549 Rat
|PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.|
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Western blot analysis of PPAPDC2 in Raji cell lysate with PPAPDC2 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
Immunofluorescence of PPAPDC2 in Raji cells with PPAPDC2 antibody at 20 ug/mL.