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Home Antibody All anti-TBKBP1 antibodies

Anti-TBKBP1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306842 Rabbit Polyclonal Prosapip2 Antibody 100ug $325 3-7 Days
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Also for TBKBP1 (NM_014726)
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OriGene Data

ImmunogenProsapip2 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human Prosapip2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameTBK1 binding protein 1
Alternative NameProSAPiP2|SINTBAD
Database LinkNP_055541
Entrez Gene 9755 Human
Entrez Gene 73174 Mouse
Entrez Gene 266764 Rat
FunctionProsapip2 (TBKBP1) is essential for signal transduction during viral infection thus plays a major role in the TNF/NF-kappaB pathway. It is an adaptor protein that constitutively binds TBK1 (TANK-binding kinase) and IKBKE and may play a role in antiviral innate immunity. Prosapip2 is a 615 amino acid adaptor protein belonging to the fibrillar collagen family, consisting of trimers of identical alpha 1 chains which are linked to each other by interchain disulfide bonds. It has a ubiquitous expression with highest levels in ovary, followed by the neuronal system. Prosapip2 binds to TBK1 and helps in the activation of IRF3 which controls the expression of antiviral genes during infection. Recent studies show that Prosapip2 is an interaction partner of ProSAP2/Shank3 and actin, suggesting a role as a linker molecule between postsynaptic density and the cytoskeleton.
Related Pathway RIG-I-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Prosapip2 in rat liver tissue lysate with Prosapip2 antibody at 1 µg/ml.

IHC Image
Immunohistochemistry of Prosapip2 in rat liver tissue with Prosapip2 antibody at 5 ug/ml.

IF Image
Immunofluorescence of Prosapip 2 in rat liver tissue with Prosapip 2 antibody at 20 ug/mL.


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