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Home Antibody All anti-AGTR1 antibodies

Anti-AGTR1 Antibody

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SKU Description Amount Price Availability*  
TA306839
  • Rabbit Polyclonal AGTR1 Antibody
100ug 325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenAGTR1 antibody was raised against a 16 amino acid peptide from near the center of human AGTR1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens angiotensin II receptor, type 1 (AGTR1), transcript variant 1
Alternative NameAG2S; AGTR1B; AT1; AT1AR; AT1B; AT1BR; AT1R; AT2R1; HAT1R
Database LinkNP_000676
FunctionAngiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. AGTR1, the type 1 receptor, is thought to mediate the major cardiovascular effects of angiotensin II and may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. AGTR1 has recently been found to regulate the differentiation of bone marrow-derived monocyte lineage progenitors from hematopoietic stem cells, indicating the diversity of the roles of AGTR1.
Related Pathway
Signaling by GPCR

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WB Image
Western blot analysis of AGTR1 in mouse kidney tissue lysate with AGTR1 antibody at (A) 1 and (B) 2 µg/ml.
IHC Image
Immunohistochemistry of AGTR1 in mouse kidney tissue with AGTR1 antibody at 2.5 ug/ml.

 

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