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Home Antibody All anti-RIPK1 antibodies

Anti-RIPK1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306838
  • Rabbit Polyclonal RIPK1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401251) , 20ug
100ug 325 In Stock
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WB(1)
IHC(1)
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Also for RIPK1 (NM_003804)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRIPK1 antibody was raised against a 15 amino acid peptide from near the amino terminus of human RIPK1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens receptor (TNFRSF)-interacting serine-threonine kinase 1 (RIPK1)
Alternative NameRIP; RIP1
Database LinkNP_003795
FunctionRIPK1 (Receptor Interacting Protein) is a crucial 74 kD adaptor kinase in several of stress-induced signaling pathways and on the crossroad of a cell’s decision to live or die. RIPK1 contains an N-terminal region with homology to protein kinases, an intermediate domain capable of association with MAPKKK and a C-terminal region containing a death domain motif present in the Fas and TNFR1 intracellular domains. Full length RIPK1 is important for signallling to NF-kappa-B, MAPKs and necrosis, whereas caspase-8 generates a C-terminal RIPK1 cleavage fragment, promoting TNF-induced apoptosis. It is required for TNFRSF1A-mediated and TLR3-induced NF-kappa-B activation. RIPK1-deficient mice fail to thrive, displaying extensive apoptosis in both lymphoid and adipose tissues and dying at 1-3 days of age.
Related Pathway
Apoptosis
EGFR1 Signaling Pathway
Toll-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of RIPK1 in rat kidney tissue lysate with RIPK1 antibody at 1 µg/ml.</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>
IHC Image
Immunohistochemistry of RIPK1 in mouse kidney tissue with RIPK1 antibody at 2.5 ug/ml.</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>

 

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