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Home Antibody All anti-JMJD1C antibodies

Anti-JMJD1C Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306830 Rabbit Polyclonal JMJD1C Antibody 100ug $325 3 Weeks
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OriGene Data

ImmunogenJMJD1C antibody was raised against a 20 amino acid peptide from near the amino terminus of human JMJD1C.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target Namejumonji domain containing 1C
Alternative NameTRIP-8|TRIP8
Database Link-
Entrez Gene 221037 Human
Entrez Gene 108829 Mouse
Entrez Gene 171120 Rat
FunctionThe jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico, and later suggested to be a candidate gene for autism. Like the related proteins JMJD1A and JMJD1B, JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation. JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet, diffuse-type gastric cancer, and other tissues and tumors. The JMJD1C gene promoter contain bHLH-, AP-1-, and POU5F1-binding sites, and as preferential expression of POU5F1 has been reported in ES cells, pancreatic islet, and diffuse-type gastric cancer, it has been suggested that POU5F1-mediated expression of JMJD1C reactivates previously silenced genes in ES cells and diffuse-type gastric cancer. At least three isoforms of JMJD1C are known to exist. This antibody will not cross-react with JMJD1A or JMJD1B.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of JMJD1C in human liver tissue lysate with JMJD1C antibody at (A) 1 and (B) 2 µg/ml.

IHC Image
Immunohistochemistry of JMJD1C in rat liver tissue with JMJD1C antibody at 2.5 ug/ml.

IF Image
Immunofluorescence of JMJD1C in rat liver tissue with JMJD1C antibody at 20 ug/mL.


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