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Home Antibody All anti-FAM120A antibodies

Anti-FAM120A Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306826 Rabbit Polyclonal FAM120A Antibody 100ug $325 3-7 Days
LC415164 FAM120A HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenFAM120A antibody was raised against an 18 amino acid peptide from near the center of human FAM120A.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 0.5 - 1 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target Namefamily with sequence similarity 120A
Alternative NameC9orf10|DNAPTP1|DNAPTP5|OSSA
Database LinkNP_055427
Entrez Gene 23196 Human
Entrez Gene 218236 Mouse
Entrez Gene 291019 Rat
FunctionFAM120A (C9orf10) is a member of the constitutive coactivator of PPAR gamma family and the gene was mapped to chromosome 9q22.31. FAM120A was recently detected within the Pur-alpha-containing mRNA-protein complex in the brain. As a novel RNA-binding protein, FAM120A is a critical component of the oxidative stress-induced survival signaling. It may participate in mRNA transport in the cytoplasm. FAM120A activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A protects cells from apoptosis through activation of SRKs in response to oxidative stress. Blocking of the survival signaling mediated by FAM120A, which sensitizes the cancer cells to stress-induced apoptosis, may be a novel therapeutic approach for gastric scirrhous carcinoma cells. This antibody will not cross-reacti with FAM120B / PGCC1.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of FAM120A in SK-N-SH cell lysate with FAM120A antibody at (A) 0.5 and (B) 1 µg/ml.

IHC Image
Immunohistochemistry of FAM120A in rat brain tissue with FAM120A antibody at 2.5 ug/ml.

IF Image
Immunofluorescence of FAM120A in Rat Brain cells with FAM120A antibody at 20 ug/mL.


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