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Home Antibody All anti-MAK10 antibodies

Anti-MAK10 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306812 Rabbit Polyclonal MAK10 Antibody 100ug $325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenMAK10 antibody was raised against a 19 amino acid peptide near the amino terminus of human MAK10.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens N(alpha)-acetyltransferase 35, NatC auxiliary subunit (NAA35)
Alternative NamebA379P1.1; EGAP; MAK10; MAK10P
Database LinkNP_078911
Entrez Gene 60560 Human
Entrez Gene 78689 Mouse
Entrez Gene 64472 Rat
FunctionThe MAK10 gene encodes a 733-amino acid protein with several regions of similarity to T cell receptor alpha-subunit V (variable) regions in yeast. The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) that is highly conserved among vertebrate species. It is expressed in a variety of tissues in the developing rat embryo but restricted in expression in the adult, remaining detectable only in tissues undergoing continual cell renewal or in cells responding to pathological injury. The MAK10-NAT complex is an essential regulatory enzyme controlling the function of a subset of proteins required for embryonic growth control and vessel development. This complex functionally co-assembles in mammalian cells to regulate cell proliferation and is essential for embryonic development, at least in part through the regulation of target of rapamycin (TOR) signaling events. At least two isoforms of MAK10 are known to exist.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of MAK10 in rat heart tissue lysate with MAK10 antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.
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Immunohistochemistry of MAK10 in human heart tissue with MAK10 antibody at 2.5 ug/ml.
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