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Home Antibody All anti-RGS21 antibodies

Anti-RGS21 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306792 Rabbit Polyclonal RGS21 Antibody 100ug $325 3-7 Days
LC422023 RGS21 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRGS21 antibody was raised against a 16 amino acid peptide near the center of human RGS21.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 0.5 ug/mL, IF: 20 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens regulator of G-protein signaling 21 (RGS21)
Alternative Name
Database LinkNP_001034241
Entrez Gene 431704 Human
FunctionRegulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit. RGS21 is a recently identified member of this family that has been reported to be selectively expressed in subpopulations of taste bud cells and co-expressed with bitter and sweet transduction components such as alpha-gusticin, phospholipase Cbeta2, T1R2/T1R3 sweet taste receptors and T2R bitter taste receptors. Other reports indicate that RGS21 is more widely expressed. Binding assays demonstrate that RGS21 binds alpha-gusticin in a conformation-dependent manner and may do the same with T1R receptors, suggesting that RGS21 may play a role in sweet and bitter taste transduction processes.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of RGS21 in HepG2 cell lysate with RGS21 antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide.

IF Image
Immunocytochemistry of RGS21 in HepG2 cells with RGS21 antibody at 2.5 ug/mL.

IF Image
Immunofluorescence of RGS21 in HepG2 cells with RGS21 antibody at 20 ug/mL.


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