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Home Antibody All anti-RUNX1 antibodies

Anti-RUNX1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306772
  • Rabbit Polyclonal RUNX1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424261) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for RUNX1 (NM_001001890)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRUNX1 antibody was raised against a 16 amino acid peptide from near the center of human RUNX1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens runt-related transcription factor 1 (RUNX1), transcript variant 2
Alternative NameAML1; AML1-EVI-1; AMLCR1; CBFA2; EVI-1; PEBP2aB
Database LinkNP_001001890
FunctionRUNX1 is one of three mammalian RUNX genes that control multiple aspects of embryonic development and are responsible for the pathogenesis of many human diseases. RUNX1 plays major roles in the development of nociceptive sensory neurons in addition to hematopoietic stem cells (HSC) with the exception of the erythroid lineage. During development, Notch signals mediate RUNX1 induction with SCL/GATA/Ets factors, and Wnt signals potentially cooperate with RUNX1 to facilitate adult HSC expansion via cooperative induction of cyclin D, cdk4, and other cell cycle regulators. In turn, RUNX1 regulates cell cycle transitions dependent on functional/physical interactions with other proteins such as HDAC1 and -3, mSin3A, p300, SMAD proteins, and LEF/TCF.
Related Pathway

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WB Image
Western blot analysis of RUNX1 in Raji cell lysate with RUNX1 antibody at (A) 1 and (B) 2 µg/ml.

 

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