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Home Antibody All anti-MATN3 antibodies

Anti-MATN3 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306768 Rabbit Polyclonal MATN3 Antibody 100ug $325 3-7 Days
LC419366 MATN3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IF(1)
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Also for MATN3 (NM_002381)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenMATN3 antibody was raised against a 13 amino acid peptide from near the center of human MATN3.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/ml, ICC: 2.5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens matrilin 3 (MATN3)
Alternative NameDIPOA; EDM5; HOA; OADIP; OS2
Database LinkNP_002372
Entrez Gene 4148 Human
Entrez Gene 17182 Mouse
Entrez Gene 313954 Rat
FunctionMatrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.
Related PathwaySecreted ProteinDruggable Genome

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* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of MATN3 in rat thymus tissue lysate with MATN3 antibody at (A) 1 and (B) 2 ug/mL.
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Immunocytochemistry of MATN3 in 3T3 cells tissue with MATN3 antibody at 2.5 ug/mL.
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