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Home Antibody All anti-MATN1 antibodies

Anti-MATN1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306761
  • Rabbit Polyclonal MATN1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419364) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenMATN1 antibody was raised against a 13 amino acid peptide from near the carboxy terminus of human MATN1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens matrilin 1, cartilage matrix protein (MATN1)
Alternative NameCMP; CRTM
Database LinkNP_002370
Entrez Gene 4146 Human
Entrez Gene 17180 Mouse
Entrez Gene 297894 Rat
FunctionMatrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of MATN1 in rat liver tissue lysate with MATN1 antibody at (A) 1 and (B) 2 ug/ml.
IHC Image
Immunohistochemistry of MATN1 in human liver tissue with MATN1 antibody at 5 ug/ml.

 

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