Home Antibody All anti-PCDH12 antibodies
Also for PCDH12 (NM_016580)
|PCDH12 antibody was raised against a 17 amino acid peptide near the amino terminus of human PCDH12.|
|Human, Mouse, Rat
||WB: 1 - 2 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens protocadherin 12 (PCDH12)|
Entrez Gene 51294 Human
Entrez Gene 53601 Mouse
Entrez Gene 116808 Rat
|Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA; further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2,289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling. This antibody is predicted to not cross-react with PCDH18.|
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Western blot analysis of PCDH12 in K562 cell lysate with PCDH12 antibody at 2 ug/ml.
Immunohistochemistry of PCDH12 in rat lung tissue with PCDH12 antibody at 5 ug/ml.