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Home Antibody All anti-PCDH12 antibodies

Anti-PCDH12 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306741 Rabbit Polyclonal PCDH12 Antibody 100ug $325 2 Weeks
LC413902 PCDH12 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for PCDH12 (NM_016580)
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OriGene Data

ImmunogenPCDH12 antibody was raised against a 17 amino acid peptide near the amino terminus of human PCDH12.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 2 ug/mL, ICC: 5 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target Nameprotocadherin 12
Alternative NameVE-cadherin-2|VECAD2
Database LinkNP_057664
Entrez Gene 51294 Human
Entrez Gene 53601 Mouse
Entrez Gene 116808 Rat
FunctionProtocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA; further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2,289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling. This antibody is predicted to not cross-react with PCDH18.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of PCDH12 in K562 cell lysate with PCDH12 antibody at 2 ug/ml.

IHC Image
Immunohistochemistry of PCDH12 in rat lung tissue with PCDH12 antibody at 5 ug/ml.


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