Home Antibody All anti-GNPDA1 antibodies
Also for GNPDA1 (NM_005471)
|GNPDA1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human GNPDA1.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml, ICC: 5 ug/ml, IF: 20 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens glucosamine-6-phosphate deaminase 1 (GNPDA1)|
|GNP1; GNPDA; GNPI; GPI; HLN|
Entrez Gene 10007 Human
Entrez Gene 26384 Mouse
Entrez Gene 683570 Rat
|Glucosamine-6-phosphate deaminase (GNPDA) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. GNPDA1 is one of two mammalian glucosamine-6-phosphate deaminases that are thought to have arisen though gene duplication, with the GNPDA2 protein closer in structure and activity to the E. coli enzyme. GNPDA1 possesses greater affinity for ammonium than either GNPDA2 or the E. coli enzyme suggesting that the forward reaction of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium is catalyzed at a slower rate than GNPDA2. GNPDA1 is predicted to not cross-react with GNPDA2.|
| Amino sugar and nucleotide sugar metabolismMetabolic pathways|
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Western blot analysis of GNPDA1 in mouse kidney lysate with GNPDA1 antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry of GNPDA1 in 293 cells with GNPDA1 antibody at 5 ug/mL.