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Home Antibody All anti-GNPDA1 antibodies

Anti-GNPDA1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306732
  • Rabbit Polyclonal GNPDA1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417282) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for GNPDA1 (NM_005471)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenGNPDA1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human GNPDA1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, ICC: 5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens glucosamine-6-phosphate deaminase 1 (GNPDA1)
Alternative NameGNP1; GNPDA; GNPI; GPI; HLN
Database LinkNP_005462
Entrez Gene 10007 Human
Entrez Gene 26384 Mouse
Entrez Gene 683570 Rat
FunctionGlucosamine-6-phosphate deaminase (GNPDA) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. GNPDA1 is one of two mammalian glucosamine-6-phosphate deaminases that are thought to have arisen though gene duplication, with the GNPDA2 protein closer in structure and activity to the E. coli enzyme. GNPDA1 possesses greater affinity for ammonium than either GNPDA2 or the E. coli enzyme suggesting that the forward reaction of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium is catalyzed at a slower rate than GNPDA2. GNPDA1 is predicted to not cross-react with GNPDA2.
Related Pathway Amino sugar and nucleotide sugar metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of GNPDA1 in mouse kidney lysate with GNPDA1 antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunocytochemistry of GNPDA1 in 293 cells with GNPDA1 antibody at 5 ug/mL.

 

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