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Home Antibody All anti-FNIP2 antibodies

Anti-FNIP2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306730
  • Rabbit Polyclonal FNIP2 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC412262) , 20ug Explanation
100ug 325 In Stock
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WB(1)
IHC(1)
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Also for FNIP2 (NM_020840)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFNIP2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human FNIP2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsELISA, WB: 1 - 2 ug/ml, IHC: 5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens folliculin interacting protein 2 (FNIP2)
Alternative NameFNIPL; MAPO1
Database LinkNP_065891
Entrez Gene 57600 Human
Entrez Gene 329679 Mouse
Entrez Gene 310538 Rat
FunctionFNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49% identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship. Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of FNIP2 in rat skeletal muscle lysate with FNIP2 antibody at (A) 1 and (B) 2 ug/mL.
IHC Image
Immunohistochemistry of FNIP2 in mouse skeletal muscle tissue with FNIP2 antibody at 5 ug/mL.

 

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