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Home Antibody All anti-TMEM18 antibodies

Anti-TMEM18 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306729
  • Rabbit Polyclonal TMEM18 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC407292) , 20ug
100ug $325 3-7 Days
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WB(1)
IHC(1)
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Also for TMEM18 (NM_152834)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenTMEM18 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human TMEM18.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsELISA, WB: 0.5 - 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens transmembrane protein 18 (TMEM18)
Alternative NameDKFZp434C1714
Database LinkNP_690047
FunctionRecent studies have examined how overexpression of certain genes enhances the tropism of neural stem cells (NSCs) for gliomas. Overexpression of Transmembrane protein 18 (TMEM18) provides NSCs and neural precursors an increased migration capacity towards glioblastoma cells in vitro and in the rat brain, while functional inactivation of the gene resulted in an almost complete loss of migration activity, suggesting that TMEM18 could be a potential target in NSC-based glioma therapy. Other recent results suggest that among others, the TMEM18 loci is associated with higher than normal body mass index (BMI) and obesity, indicating there may be a CNS-related role in predisposition to obesity. Multiple isoforms of TMEM18 are known to exist.
Related Pathway

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WB Image
Western blot analysis of TMEM18 in rat brain lysate with TMEM18 antibody at (A) 0.5 and (B) 1 ug/mL.
IHC Image
Immunohistochemistry of TMEM18 in mouse brain tissue with TMEM18 antibody at 2.5 ug/mL.

 

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