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Home Antibody All anti-LASS6 antibodies

Anti-LASS6 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306689 Rabbit Polyclonal LASS6 Antibody 100ug $325 3-7 Days
LC404278 CERS6 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for LASS6 (NM_203463)
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OriGene Data

ImmunogenLASS6 antibody was raised against a 13 amino acid peptide near the amino terminus of the human LASS6.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens ceramide synthase 6 (CERS6), transcript variant 2
Alternative NameCERS5; LASS6
Database LinkNP_982288
Entrez Gene 253782 Human
Entrez Gene 241447 Mouse
Entrez Gene 366065 Rat
FunctionThe LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. Like the highly homologous LASS5, LASS6 is also an endoplasmic reticulum, multi-pass membrane protein. LASS6 is also involved in the synthesis of C14, C16 and C18-ceramide, but shows a preference for unsaturated fatty acids. LASS6 is broadly expressed in a wide range of tissues and microarray data suggests that it may play a role in cancer differentiation and early embryonic development. At least two isoforms of LASS6 are known to exist. This antibody is predicted not to cross-react with LASS5.
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of LASS6 in rat brain tissue lysate with LASS6 antibody at (A) 1 and (B) 2 ug/ml.

IHC Image
Immunohistochemistry of LASS6 in mouse brain tissue with LASS6 antibody at 2.5 ug/ml.

IF Image
Immunofluorescence of LASS6 in Mouse Brain cells with LASS6 antibody at 5 ug/mL.


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