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Home Antibody All anti-STK39 antibodies

Anti-STK39 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306670 Rabbit Polyclonal Stk39 Antibody 100ug $325 3-7 Days
LC402227 STK39 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for STK39 (NM_013233)
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OriGene Data

ImmunogenStk39 antibody was raised against a 18 amino acid peptide from near the center of human Stk39.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/mL, ICC: 2.5 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens serine threonine kinase 39 (STK39)
Alternative NameDCHT; PASK; SPAK
Database LinkNP_037365
Entrez Gene 27347 Human
Entrez Gene 53416 Mouse
Entrez Gene 54348 Rat
FunctionThe serine/threonine kinase Stk39 belongs to the STE20 family, a group of kinases that are known to interact with inflammation-related kinases (such as p38, JNK, NKCC1, PKC-theta, WNK and MLCK), and with transcription factor AP-1. The STE 20 family is involved in diverse biological phenomena, including cell differentiation, cell transformation/ proliferation, cytoskeleton rearrangement, and the regulation of ion transporters. STK39 contains an N-terminal series of proline and alanine repeats (PAPA box), followed by a serine/threonine kinase catalytic domain and is abundantly expressed in the brain. STK39 is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled co-transporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. Recent studies show that STK39 tend to be a novel candidate gene for autism and hypertension.
Related PathwayProtein KinaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Stk39 in rat brain tissue lysate with Stk39 antibody at (A) 1 and (B) 2 ug/ml.

IHC Image
Immunohistochemistry of Stk39 in human brain tissue with Stk39 antibody at 2.5 ug/ml.


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