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Home Antibody All anti-MEX3C antibodies

Anti-MEX3C Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306667
  • Rabbit Polyclonal Rkhd2 Antibody
100ug $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenRkhd2 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human RKHD2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens mex-3 RNA binding family member C (MEX3C)
Alternative NameBM-013; MEX-3C; RKHD2; RNF194
Database LinkNP_057710
FunctionRkhd2, also known as MEX3C is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd2, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. It has been suggested that genetic variations in Rkhd2 may be associated with susceptibility to essential hypertension type 8. Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
Related Pathway

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WB Image
Western blot analysis of Rkhd2 in rat heart tissue lysate with Rkhd2 antibody at (A) 0.5 µg/ml and (B) 1 µg/ml.

 

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