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Home All anti-ZNF350 antibodies
Anti-ZNF350 Antibody
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for ZNF350 (NM_021632)
OriGene Data
| ZBRK1 antibody was raised against a 20 amino acid peptide near the carboxy terminus of the human ZBRK1. |
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IgG |
| Human, Mouse, Rat |
1ug/ul |
| WB |
WB: 1 - 2 ug/ml |
| PBS containing 0.02% sodium azide. |
| Affinity chromatography purified via peptide column (Protein A or G Sepharose) |
Reference Data
| Homo sapiens zinc finger protein 350 (ZNF350) |
| ZBRK1; ZFQR |
| NP_067645 |
| ZBRK1 is a member of the Kruppel-associated box-zinc finger protein (KRAB-ZFP) protein family of transcriptional repressors. ZBRK1 has been shown to not only be up-regulated in senescent fibroblasts but also interacts with BRCA1, a transcriptional regulator with tumor suppressor activity. ZBRK1 binds to a specific sequence within the GADD45 gene, supporting the assembly of a nuclear complex containing BRCA1 and repressing its transcription. Recent experiments demonstrate that ZBRK1 can homo-oligomerize in vitro and in vivo through a C-terminal transcriptional repression domain (CTRD), and this oligomerization facilitates the ZBRK1-directed transcriptional repression through ZBRK1 response elements. These results suggest that higher order ZBRK1 oligomers may assemble through both protein-DNA and CTRD-dependent protein-protein interactions. |
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* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Western blot analysis of ZBRK1 in A-20 lysate with ZBRK1 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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