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Home Antibody All anti-HINT1 antibodies

Anti-HINT1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306652
  • Rabbit Polyclonal HINT1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417372) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for HINT1 (NM_005340)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenHINT1 antibody was raised against a 17 amino acid peptide near the center of the human HINT1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, ICC: 2.5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens histidine triad nucleotide binding protein 1 (HINT1), transcript variant 1
Alternative NameHINT; NMAN; PKCI-1; PRKCNH1
Database LinkNP_005331
Entrez Gene 3094 Human
Entrez Gene 15254 Mouse
Entrez Gene 690660 Rat
FunctionHistidine triad nucleotide-binding protein 1 (HINT1) is a member of the histidine triad (HIT) protein family, a group of small nucleotide-binding and –hydrolyzing proteins. HINT1 interacts with several diverse proteins and has been suggested to have tumor suppressive activities. HINT1 catalyzes the hydrolysis of adenosine 5’-monophoramidate substrates such as AMP-morpholidate, but its enzymatic function does not appear to play a role in its tumor suppression. Recent experiments demonstrate that HINT1 forms a complex with POSH and JNK in vivo, inhibiting AP-1 activity and the phosphorylation of c-Jun, and this action could contribute to the tumor suppressor activity of HINT1. Other studies raise the possibility of HINT1 as a candidate gene for schizophrenia.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of HINT1 in Jurkat lysate with HINT1 antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunocytochemistry of HINT1 in Jurkat cells with HINT1 antibody at 2.5 ug/mL.

 

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