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Home Antibody All anti-ALDH5A1 antibodies

Anti-ALDH5A1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306648
  • Rabbit Polyclonal Aldh5A1 Antibody
100ug $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenAldh5A1 antibody was raised against a 22 amino acid peptide near the carboxy terminus of the human Aldh5A1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens aldehyde dehydrogenase 5 family, member A1 (ALDH5A1), transcript variant 2
Alternative NameSSADH; SSDH
Database LinkNP_001071
FunctionAldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.
Related Pathway

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WB Image
Western blot analysis of Aldh5A1 in mouse liver lysate with Aldh5A1 antibody at (A) 1 and (B) 2 µg/ml.

 

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