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Home Antibody All anti-IL34 antibodies

Anti-IL34 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306635 Rabbit Polyclonal IL-34 Antibody 100ug $325 3-7 Days
LC432749 IL34 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenIL-34 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-34.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 0.25 - 0.5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens interleukin 34 (IL34), transcript variant 2
Alternative NameC16orf77; IL-34
Database LinkNP_001166242
Entrez Gene 146433 Human
Entrez Gene 76527 Mouse
Entrez Gene 498951 Rat
FunctionInterleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages. Despite its predicted molecular weight, IL-34 will often run at higher molecular weight in SDS-PAGE.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of IL-34 in human brain tissue lysate with IL-34 antibody at 0.25 µg/ml in (A) the absence and (B) the presence of blocking peptide.


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