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Home Antibody All anti-PRTFDC1 antibodies

Anti-PRTFDC1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306634
  • Rabbit Polyclonal PRTFDC1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC412622) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for PRTFDC1 (NM_020200)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPRTFDC1 antibody was raised against a 14 amino acid peptide from near the center of human PRTFDC1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens phosphoribosyl transferase domain containing 1 (PRTFDC1), transcript variant 1
Alternative NameHHGP
Database LinkNP_064585
Entrez Gene 56952 Human
Entrez Gene 291355 Rat
FunctionPhosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of PRTFDC1 in human brain tissue lysate with PRTFDC1 antibody at 1 µg/ml in the (A) absence and (B) presence of blocking peptide.

 

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