Home Antibody All anti-NENF antibodies
Also for NENF (NM_013349)
|NENF antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human NENF.|
|Human, Mouse, Rat
||WB: 1 - 2 ug/ml, IHC: 10 ug/ml, IF: 20 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens neudesin neurotrophic factor (NENF), transcript variant 1|
|CIR2; SCIRP10; SPUF|
|NENF is a secreted protein that is expressed in neurons but not glial cells of the brain. This protein has neurotrophic activity in primary cultured mouse neurons but not mitogenic activity in primary cultured mouse astrocytes. NENF activated mitogen-activated protein (MAP) and phosphotidylinositol-3 kinase pathways and could be inhibited by pertussis toxin but not receptor tyrosine kinases, suggesting that NENF acts through a Gi/Go-protein-coupled receptor. Despite its predicted molecular weight of ~20kDa, NENF is observed at 37kDa in SDS-PAGE.|
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Western blot analysis of NENF in human kidney tissue lysate with NENF antibody at (A) 1 and (B) 2 ug/ml.
Immunohistochemistry of NENF in rat kidney tissue with NENF antibody at 10 ug/ml.