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Anti-NENF Antibody


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SKU Description Amount Price Availability*  
  • Rabbit Polyclonal NENF Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC415653) , 20ug Explanation
100ug $325 3-7 Days
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OriGene Data

ImmunogenNENF antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human NENF.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml, IHC: 10 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens neudesin neurotrophic factor (NENF), transcript variant 1
Alternative NameCIR2; SCIRP10; SPUF
Database LinkNP_037481
Entrez Gene 29937 Human
Entrez Gene 66208 Mouse
Entrez Gene 289380 Rat
FunctionNENF is a secreted protein that is expressed in neurons but not glial cells of the brain. This protein has neurotrophic activity in primary cultured mouse neurons but not mitogenic activity in primary cultured mouse astrocytes. NENF activated mitogen-activated protein (MAP) and phosphotidylinositol-3 kinase pathways and could be inhibited by pertussis toxin but not receptor tyrosine kinases, suggesting that NENF acts through a Gi/Go-protein-coupled receptor. Despite its predicted molecular weight of ~20kDa, NENF is observed at 37kDa in SDS-PAGE.
Related PathwaySecreted ProteinDruggable Genome

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WB Image
Western blot analysis of NENF in human kidney tissue lysate with NENF antibody at (A) 1 and (B) 2 ug/ml.
IHC Image
Immunohistochemistry of NENF in rat kidney tissue with NENF antibody at 10 ug/ml.


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