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Anti-HAX1 Antibody

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

OriGene Data

Immunogen	Hax1b antibody was raised against a 10 amino acid peptide near the amino terminus of human Hax1b.
Clone Name		Isotype	IgG
Species Reactivity	Human, Mouse, Rat	Concentration	1ug/ul
Guaranteed Application *	WB	Suggested Dilutions	WB: 1 - 2 ug/ml
Buffer	PBS containing 0.02% sodium azide.
Purification	Affinity chromatography purified via peptide column (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens HCLS1 associated protein X-1 (HAX1), transcript variant 2
Alternative Name	HCLSBP1; HS1BP1; SCN3
Database Link	NP_001018238
Function	The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting. At least four isoforms of Hax1 are known to exist. This antibody is predicted to recognize Hax1b.
Related Pathway

Related Lysate from OriGene • Transient overexpression lysate of HCLS1 associated protein X-1 (HAX1), transcript variant 2 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • HAX1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • HAX1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Hax1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • HAX1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Hax1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens HCLS1 associated protein X-1 (HAX1), transcript variant 2 as transfection-ready DNA • Lenti ORF clone of Human HCLS1 associated protein X-1 (HAX1), transcript variant 2, mGFP tagged • Lenti ORF clone of Human HCLS1 associated protein X-1 (HAX1), transcript variant 2 , Myc-DDK-tagged • GFP-tagged ORF clone of Homo sapiens HCLS1 associated protein X-1 (HAX1), transcript variant 2 as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens HCLS1 associated protein X-1 (HAX1), transcript variant 2 as 200 ug transfection-ready DNA Related cDNA Clones • Homo sapiens HCLS1 associated protein X-1 (HAX1), transcript variant 2 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)