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Home Antibody All anti-NUP107 antibodies

Anti-NUP107 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306612
  • Rabbit Polyclonal NUP107 Antibody
100ug $325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenNUP107 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human NUP107.
Clone Name IsotypeIgG
Species ReactivityHuman, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, ICC: 2.5 ug/ml, IF: 10 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens nucleoporin 107kDa (NUP107)
Alternative NameNUP84
Database LinkNP_065134
FunctionThe nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.
Related Pathway
Cell cycle

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WB Image
Western blot analysis of NUP107 in A549 cell lysate with NUP107 antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunocytochemistry of NUP107 in A549 cells with NUP107 antibody at 2.5 ug/mL.

 

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