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Home Antibody All anti-CLIP1 antibodies

Anti-CLIP1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306599
  • Rabbit Polyclonal CLIP170 Antibody
100ug 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenCLIP170 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human CLIP170.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 0.5 - 1 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens CAP-GLY domain containing linker protein 1 (CLIP1), transcript variant 1
Alternative NameCLIP; CLIP-170; CLIP170; CYLN1; RSN
Database LinkNP_002947
Entrez Gene 6249 Human
Entrez Gene 56430 Mouse
Entrez Gene 65201 Rat
FunctionCLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin’s disease. Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles. CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein/dynactin binding microtubules. Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1. At least two isoforms of CLIP170 are known to exist.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of CLIP170 in rat brain tissue lysate with CLIP170 antibody at (A) 0.5 and (B) 1 ug/mL.
IF Image
Immunofluorescence of CLIP170 in human brain tissue with CLIP170 antibody at 20 ug/mL.

 

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