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Home Antibody All anti-WNT10B antibodies

Anti-WNT10B Antibody


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SKU Description Amount Price Availability*  
TA306582 Rabbit Polyclonal Wnt10b Antibody 100ug $325 In Stock
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OriGene Data

ImmunogenWnt10b antibody was raised against a 15 amino acid peptide from near the center of human Wnt10b.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 2 - 4 ug/mL, ICC: 2.5 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameWnt family member 10B
Alternative NameSHFM6|WNT-12
Database LinkNP_003385
Entrez Gene 7480 Human
Entrez Gene 22410 Mouse
Entrez Gene 315294 Rat
FunctionWnt10b is a member of the Wnt family, a gene family that encodes secreted signaling proteins that play crucial roles in normal development such as regulation of cell fate and patterning during embryogenesis as well as neoplastic transformation. Wnt10b is found in the mouse mammary tumor virus insertion site where it is activated and causes mammary tumors. Elevated levels of Wnt10b have also been detected in human breast carcinomas. Wnt10b is known to be involved in adipogenesis, maintaining the preadipocyte in an undifferentiated state. More recently, Wnt10b has been shown to promote epithelial cell differentiation and hair shaft growth, demonstrating that Wnt10b has multiple roles in cell growth and differentiation. Two isoforms of Wnt10b are known to exist; this antibody will only recognize the longer isoform. This Wnt10b antibody will not cross-react with Wnt10a.
Related PathwaySecreted ProteinDruggable Genome Wnt signaling pathwayHedgehog signaling pathwayMelanogenesisPathways in cancerBasal cell carcinoma

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Wnt10b in human skeletal muscle tissue lysate with Wnt10b antibody at (A) 2 and (B) 4 ug/ml.

IHC Image
Immunohistochemistry of Wnt10b in human skeletal muscle with Wnt10b antibody at 2.5 ug/ml.


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