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Home Antibody All anti-ELOVL6 antibodies

Anti-ELOVL6 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306564
  • Rabbit Polyclonal ELOVL6 Antibody
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for ELOVL6 (NM_001130721)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenELOVL6 antibody was raised against a 16 amino acid peptide near the amino terminus of the human ELOVL6.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens ELOVL fatty acid elongase 6 (ELOVL6), transcript variant 2
Alternative NameFACE; FAE; LCE
Database LinkNP_001124193
FunctionLipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.
Related Pathway

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WB Image
Western blot analysis of ELOVL6 in Human brain tissue lysate with ELOVL6 antibody at (A) 1 and (B) 2 ug/ml.
IHC Image
Immunohistochemistry of ELOVL6 in human brain with ELOVL6 antibody at 5 ug/ml.

 

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