Home Antibody All anti-ELOVL6 antibodies
Also for ELOVL6 (NM_001130721)
|ELOVL6 antibody was raised against a 16 amino acid peptide near the amino terminus of the human ELOVL6.|
|Human, Mouse, Rat
||WB: 1 - 2 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens ELOVL fatty acid elongase 6 (ELOVL6), transcript variant 2|
|FACE; FAE; LCE|
Entrez Gene 79071 Human
Entrez Gene 170439 Mouse
Entrez Gene 171402 Rat
|Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.|
|Transmembrane Biosynthesis of unsaturated fatty acids|
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Western blot analysis of ELOVL6 in Human brain tissue lysate with ELOVL6 antibody at (A) 1 and (B) 2 ug/ml.
Immunohistochemistry of ELOVL6 in human brain with ELOVL6 antibody at 5 ug/ml.