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Home Antibody All anti-BAIAP3 antibodies

Anti-BAIAP3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306542
  • Rabbit Polyclonal BAP3 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418343) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for BAIAP3 (NM_003933)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenBAP3 antibody was raised against a 13 amino acid peptide from near the amino terminus of human BAP3.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens BAI1-associated protein 3 (BAIAP3), transcript variant 1
Alternative NameBAP3
Database LinkNP_003924
FunctionBAP3 was initially identified through interaction in a yeast two-hybrid system with the brain-specific angiogenesis inhibitor 1, a p53-target gene that encodes a seven-span transmembrane protein member of the secretin receptor family. BAP3 is predominantly expressed in the brain and possess high homology with Munc13 and synaptotagmin, suggesting that BAP3 may play a role in regulating neurotransmitter release. Recent experiments have shown that BAP3 is induced in certain tumors such as desmoplastic small round cell tumor. Ectopic expression of BAP3 in tumor cells dramatically enhances growth in low serum conditions and colony formation in soft agar, suggesting that the regulated exocytotic pathway may play a role in cancer cell proliferation. BAP3 is known to have two isoforms; this BAP3 antibody will recognize only isoform 2. Lower molecular weight bands may represent cleavage or degradation products.
Related Pathway

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WB Image
Western blot analysis of BAP3 in SK-N-SH cell lysate with BAP3 antibody at (A) 1 and (B) 2 ug/ml.
IHC Image
Immunohistochemical staining of human brain tissue using BAP3 antibody at 5 ug/ml.

 

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