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Home Antibody All anti-PLXDC2 antibodies

Anti-PLXDC2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306510
  • Rabbit Polyclonal Plxdc2 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC409939) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for PLXDC2 (NM_032812)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPlxdc2 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human Plxdc2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens plexin domain containing 2 (PLXDC2), transcript variant 1
Alternative NameTEM7R
Database LinkNP_116201
FunctionPlxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57% amino acid identity to TEM7, the most abundant tumor endothelial marker. Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung. Plxdc2 and TEM7 may be important for tumor angiogenesis in humans. Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors.
Related Pathway

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WB Image
Western blot analysis of Plxdc2 in human colon tissue lysate with Plxdc2 antibody at (A) 0.5 (B) 1 ug/ml.
IHC Image
Immunohistochemical staining of human brain tissue using Plxdc2 antibody at 2.5 ug/ml.

 

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