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Home Antibody All anti-ATG10 antibodies

Anti-ATG10 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306501
  • Rabbit Polyclonal ATG10 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC427366) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for ATG10 (NM_001131028)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenATG10 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human ATG10.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens autophagy related 10 (ATG10), transcript variant 3
Alternative NameAPG10; APG10L; pp12616
Database LinkNP_001124500
Entrez Gene 83734 Human
Entrez Gene 66795 Mouse
Entrez Gene 688555 Rat
FunctionAutophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. Another member of the autophagy protein family is ATG10, an E2-like enzyme involved in two ubiquitin-like modifications essential for autophagosome formation: ATG12-ATG5 conjugation and the modification of a soluble form of MAP-LC3, a homolog of yeast Apg8, to a membrane-bound form. ATG10 has also been shown to interact with ATG12 in human embryonic kidney cells in the presence of ATG7. Multiple isoforms of ATG10 are known to exist.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of ATG10 in SK-N-SH cell lysate with ATG10 antibody at (A) 0.5, (B) 1 and (C) 2 µg/ml.

 

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