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Anti-GPR124 Antibody

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IHC(1)

OriGene Data

Immunogen	TEM5 antibody was raised against a 14 amino acid peptide near the center of human TEM5.
Clone Name		Isotype	IgG
Species Reactivity	Human, Rat	Concentration	1ug/ul
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1 - 2 ug/ml
Buffer	PBS containing 0.02% sodium azide.
Purification	Affinity chromatography purified via peptide column (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens G protein-coupled receptor 124 (GPR124)
Alternative Name	TEM5
Database Link	NP_116166
Function	Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.
Related Pathway

Related Lysate from OriGene • Transient overexpression lysate of G protein-coupled receptor 124 (GPR124) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • GPR124 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • GPR124 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Gpr124 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • GPR124 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Gpr124 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens G protein-coupled receptor 124 (GPR124) as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens G protein-coupled receptor 124 (GPR124) as transfection-ready DNA • Lenti ORF clone of Human G protein-coupled receptor 124 (GPR124) , Myc-DDK-tagged • Lenti ORF clone of Human G protein-coupled receptor 124 (GPR124), mGFP tagged • GFP-tagged ORF clone of Homo sapiens G protein-coupled receptor 124 (GPR124) as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens G protein-coupled receptor 124 (GPR124) as transfection-ready DNA Related cDNA Clones • Homo sapiens G protein-coupled receptor 124 (GPR124) as transfection-ready DNA • Homo sapiens G protein-coupled receptor 124 (GPR124) as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)