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Home Antibody All anti-PTK7 antibodies

Anti-PTK7 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306461 Rabbit Polyclonal PTK7 Antibody 100ug $325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenPTK7 antibody was raised against a 15 amino acid peptide from near the amino terminus of human PTK7.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens protein tyrosine kinase 7 (PTK7), transcript variant PTK7-1
Alternative NameCCK-4; CCK4
Database LinkNP_002812
Entrez Gene 5754 Human
Entrez Gene 71461 Mouse
Entrez Gene 301242 Rat
FunctionProtein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist.
Related PathwayProtein KinaseTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of PTK7 in (A) human, (B) mouse and (C) rat colon tissue lysate with PTK7 antibody at 1 ug/ml.
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Immunohistochemistry of PTK7 in human colon tissue with PTK7 antibody at 5 ug/ml.
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