Home Antibody All anti-KIF5A antibodies
Also for KIF5A (NM_004984)
|KIF5 antibody was raised against a 20 amino acid peptide from near the carboxy terminus of human KIF5.|
|Human, Mouse, Rat
||ELISA, WB: 0.5 - 1 ug/ml, ICC: 5 ug/ml, IF: 20 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column (Protein A or G Sepharose)
|Homo sapiens kinesin family member 5A (KIF5A)|
|D12S1889; MY050; NKHC; SPG10|
|The kinesin superfamily proteins (KIFs) are microtubule-dependent motors that slide along microtubules and transport cellular organelles and mRNA to different parts of the cell. In neurons, KIF5 performs this role in an anterograde fashion from the neuronal cell body to axonal or dendritic terminals. KIF5 was initially differentiated from the ubiquitously expressed kinesin as being highly enriched in subsets of neurons and selectively concentrated in the cell body. KIF5 has at least three known isoforms; this antibody recognizes all three. Mutations in one of the isoforms of KIF5 (KIF5A) are thought to be involved in hereditary spastic paraplegias.|
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Western blot analysis of KIF5 in K562 cell lysate with KIF5 antibody at (A) 0.5 and (B) 1 ug/mL.
Immunocytochemistry of KIF5 in K562 cells with KIF5 antibody at 5 ug/mL.