Home Antibody All anti-IFNB1 antibodies
Also for IFNB1 (NM_002176)
|IFN-beta antibody was raised against a 17 amino acid peptide from near the center of human IFN-b.|
||WB: ~5 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens interferon, beta 1, fibroblast (IFNB1)|
|IFB; IFF; IFNB|
|Type I Interferons (IFN-a/b) are produced primarily in response to viral infection by “Natural IFN-producing cells" (IPCs) as part of the host immune response and can also inhibit the development of tumors. IFN-b binding by its receptor results in the activation of the tyrosine kinases Jak1 and Tyk2 and phosphorylation of members of the STAT family of transcription factors, leading to the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-b. IFN-b is currently used clinically for treatment of tumors, infections and multiple sclerosis.|
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Senescence and Autophagy
Toll-like receptor signaling pathway
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Western blot analysis of IFN-b in A-20 cell lysate with IFN-b antibody at 5 ug/ml.
Immunohistochemistry of IFN-? in human liver tissue with IFN-b antibody at 5 ug/ml.