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Home Antibody All anti-IFNB1 antibodies

Anti-IFNB1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306437
  • Rabbit Polyclonal IFN-beta Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400789) , 20ug
100ug $325 In Stock
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WB(1)
IHC(1)
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Also for IFNB1 (NM_002176)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenIFN-beta antibody was raised against a 17 amino acid peptide from near the center of human IFN-b.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: ~5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens interferon, beta 1, fibroblast (IFNB1)
Alternative NameIFB; IFF; IFNB
Database LinkNP_002167
FunctionType I Interferons (IFN-a/b) are produced primarily in response to viral infection by “Natural IFN-producing cells" (IPCs) as part of the host immune response and can also inhibit the development of tumors. IFN-b binding by its receptor results in the activation of the tyrosine kinases Jak1 and Tyk2 and phosphorylation of members of the STAT family of transcription factors, leading to the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-b. IFN-b is currently used clinically for treatment of tumors, infections and multiple sclerosis.
Related Pathway
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Senescence and Autophagy
Toll-like receptor signaling pathway

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WB Image
Western blot analysis of IFN-b in A-20 cell lysate with IFN-b antibody at 5 ug/ml.
IHC Image
Immunohistochemistry of IFN-? in human liver tissue with IFN-b antibody at 5 ug/ml.

 

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