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Home Antibody All anti-IFNB1 antibodies

Anti-IFNB1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306437 Rabbit Polyclonal IFN-beta Antibody 100ug $325 In Stock
LC400789 IFNB1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for IFNB1 (NM_002176)
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OriGene Data

ImmunogenIFN-beta antibody was raised against a 17 amino acid peptide from near the center of human IFN-b.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: ~5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens interferon, beta 1, fibroblast (IFNB1)
Alternative NameIFB; IFF; IFNB
Database LinkNP_002167
Entrez Gene 3456 Human
Entrez Gene 15977 Mouse
FunctionType I Interferons (IFN-a/b) are produced primarily in response to viral infection by “Natural IFN-producing cells" (IPCs) as part of the host immune response and can also inhibit the development of tumors. IFN-b binding by its receptor results in the activation of the tyrosine kinases Jak1 and Tyk2 and phosphorylation of members of the STAT family of transcription factors, leading to the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-b. IFN-b is currently used clinically for treatment of tumors, infections and multiple sclerosis.
Related PathwaySecreted ProteinTransmembraneDruggable Genome Cytokine-cytokine receptor interactionToll-like receptor signaling pathwayRIG-I-like receptor signaling pathwayCytosolic DNA-sensing pathwayJak-STAT signaling pathwayNatural killer cell mediated cytotoxicityMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of IFN-b in A-20 cell lysate with IFN-b antibody at 5 ug/ml.
Immunohistochemistry of IFN-? in human liver tissue with IFN-b antibody at 5 ug/ml.


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