Home Antibody All anti-RPAIN antibodies
Also for RPAIN (NM_001033002)
|RPA Interacting Protein antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human RPA Interacting Protein.|
|Human, Mouse, Rat
||WB: 0.5 - 1 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens RPA interacting protein (RPAIN), transcript variant 2|
Entrez Gene 84268 Human
Entrez Gene 69723 Mouse
Entrez Gene 287463 Rat
|Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import (2). Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.|
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Western blot analysis of RPA Interacting Protein in Jurkat cell lysate with RPA Interacting Protein antibody at (A) 0.5 and (B) 1 µg/ml.