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Home Antibody All anti-TIMD4 antibodies

Anti-TIMD4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306323
  • Rabbit Polyclonal TIM-4 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC431308) , 20ug
100ug $325 3-7 Days
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WB(1)
IF(1)
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Also for TIMD4 (NM_001146726)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenTIM-4 antibody was raised against a 16 amino acid peptide from near the center of human TIM-4.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens T-cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant 2
Alternative NameSMUCKLER; TIM4
Database LinkNP_001140198
FunctionThe T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.
Related Pathway

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WB Image
Western blot analysis of TIM-4 in Jurkat lysate with TIM-4 antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunocytochemistry of TIM-4 in Jurkat cells with TIM-4 antibody at 10 ug/mL.

 

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