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Home Antibody All anti-TIMD4 antibodies

Anti-TIMD4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306322
  • Rabbit Polyclonal TIM-4 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC431308) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for TIMD4 (NM_001146726)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenTIM-4 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human TIM-4.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens T-cell immunoglobulin and mucin domain containing 4 (TIMD4), transcript variant 2
Alternative NameSMUCKLER; TIM4
Database LinkNP_001140198
Entrez Gene 91937 Human
Entrez Gene 276891 Mouse
Entrez Gene 497891 Rat
FunctionThe T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TIM-4 in Jurkat lysate with TIM-4 antibody at (A) 1 and (B) 2 µg/ml.

 

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