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Home Antibody All anti-HAVCR1 antibodies

Anti-HAVCR1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306320
  • Rabbit Polyclonal TIM-1 Antibody
100ug 325 In Stock
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WB(1)
IHC(1)
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Also for HAVCR1 (NM_001099414)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenTIM-1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human TIM-1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens hepatitis A virus cellular receptor 1 (HAVCR1), transcript variant 2
Alternative NameHAVCR; HAVCR-1; KIM-1; KIM1; TIM; TIM-1; TIM1; TIMD-1; TIMD1
Database LinkNP_001092884
Entrez Gene 26762 Human
Entrez Gene 171283 Mouse
FunctionThe human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma.
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TIM-1 in human uterus tissue lysate with TIM-1 antibody at (A) 1 and (B) 2 ug/ml.
IHC Image
Immunohistochemistry of TIM-1 in human uterus tissue with TIM-1 antibody at 10 ug/ml.

 

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