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 Home All anti-CD5L antibodies

Anti-CD5L Antibody

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA306319
  • Rabbit Polyclonal AIM Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401793) , 20ug
 100ug $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
 30ul
$100
$50*		 In Stock
Add to Shopping Cart
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)
IHC(1)
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Also for CD5L (NM_005894)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenAIM antibody was raised against a 16 amino acid peptide near the amino terminus of human AIM.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column (Protein A or G Sepharose)

Reference Data

Target NameHomo sapiens CD5 molecule-like (CD5L)
Alternative NameAIM; API6; PRO229; SP-ALPHA; Spalpha
Database LinkNP_005885
FunctionApoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of AIM in human lymph node tissue lysate with AIM antibody at (A) 1, (B) 2 and (C) 4 ug/ml.
IHC Image
Immunohistochemistry of AIM in human lymph node tissue with AIM antibody at 2 ug/ml.

 

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