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Home Antibody All anti-TLR3 antibodies

Anti-TLR3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306267
  • Rabbit Polyclonal TLR3 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418801) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for TLR3 (NM_003265)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenTLR3 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human TLR3.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, ICC: 1 ug/ml, IF: 10 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens toll-like receptor 3 (TLR3)
Alternative NameCD283; IIAE2
Database LinkNP_003256
Entrez Gene 7098 Human
Entrez Gene 142980 Mouse
FunctionToll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (3) so the organism can respond to potential infection. TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection (4). Recently it has been shown to recognize viruses such as Influenza A (5) and West Nile Virus and can mediate entry of at least West Nile Virus (6).
Related PathwayTransmembraneDruggable Genome Toll-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TLR3 in Daudi cell lysate with TLR3 antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunocytochemistry of TLR3 in EL4 cells with TLR3 antibody at 1 ugg/mL.

 

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