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Home Antibody All anti-CBLN1 antibodies

Anti-CBLN1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306244
  • Rabbit Polyclonal Precerebellin Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418047) , 20ug Explanation
100ug 325 In Stock
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WB(1)
IHC(1)
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Also for CBLN1 (NM_004352)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPrecerebellin antibody was raised against a 15 amino acid peptide from the middle of human precerebellin.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 2 - 4 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens cerebellin 1 precursor (CBLN1)
Alternative Namecerebellin 1; cerebellin 1 precursor
Database LinkNP_004343
Entrez Gene 869 Human
Entrez Gene 12404 Mouse
Entrez Gene 498922 Rat
FunctionPrecerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q (1). Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka- dependent signaling pathway (2); and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release (3). The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells in cartwheel neurons of the dorsal cochlear nucleus (4). Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted proteins and has similarity to adiponectin and CTRP3, it has been suggested that precerebellin posseses functions other than those already stated (5).
Related PathwaySecreted Protein

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of precerebellin in mouse cerebellum lysate with precerebellin antibody at (A) 2 and (B) 4 ug/ml.
IHC Image
Immunohistochemical staining of rat brain tissue using precerebellin antibody at 2 ug/ml.

 

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