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Home Antibody All anti-CASP7 antibodies

Anti-CASP7 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306201 Rabbit Polyclonal Caspase-7 Antibody 100ug $325 3-7 Days
LC429055 CASP7 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenCaspase-7 antibody was raised against a 16 amino acid peptide from near the carboxy-terminus of human Caspase-7.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/mL, ICC: 2 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens caspase 7, apoptosis-related cysteine peptidase (CASP7), transcript variant a
Alternative NameCASP-7; CMH-1; ICE-LAP3; LICE2; MCH3
Database LinkNP_001218
Entrez Gene 840 Human
Entrez Gene 12369 Mouse
Entrez Gene 64026 Rat
FunctionCaspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1 and 2). The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death (reviewed in 3). Caspase-7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C. elegans cell death protein CED-3 (4). Alternative splicing of Caspase-7 mRNA results in the production of 3 distinct isoforms (4). Caspase-7 activity can be directly inhibited by XIAP expression (5).
Related PathwayProteaseDruggable Genome ApoptosisAlzheimer's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Caspase-7 in human skeletal muscle cell lysate with Caspase-7 antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.

IHC Image
Immunohistochemical staining of human skeletal muscle using caspase-7 antibody at 2 ug/ml.


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